Which of the following is a common source of infection that can lead to sepsis?

Urinary tract infections (UTIs) are a well-recognized source of infection that can lead to sepsis. UTIs occur when bacteria enter the urinary system, which includes the urethra, bladder, ureters, and kidneys. If the infection is left untreated, especially when it ascends to the kidneys, it can lead to systemic infection, prompting an inflammatory response throughout the body—this is what sepsis involves.

Factors that can increase the risk for developing sepsis from UTIs include conditions such as being elderly, having a weakened immune system, or pre-existing health conditions that affect the urinary tract. Early diagnosis and appropriate treatment are crucial to prevent the progression of a UTI to sepsis.

In contrast, while gastrointestinal issues, cardiovascular problems, and neurological disorders can contribute to a patient’s overall vulnerability to infections, they are not as directly associated with sepsis as urinary tract infections are. For instance, gastric infections can contribute to sepsis indirectly through complications, but UTIs are far more direct sources.